PEPINSKY, BLAKE: search on Z-Library

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1

Antibody humanization by redesign of complementarity-determining region residues proximate to the acceptor framework

Hanf, Karl J.M., Arndt, Joseph W., Chen, Ling Ling, Jarpe, Matthew, Boriack-Sjodin, P. Ann, Li, You, van Vlijmen, Herman W.T., Pepinsky, R. Blake, Simon, Kenneth J., Lugovskoy, Alexey

Journal:

Year:

2014

Language:

english

File:

PDF, 1.39 MB

english, 2014

2

Characterization of trisulfide modification in antibodies

Sheng Gu, Dingyi Wen, Paul H. Weinreb, Yaping Sun, Lihe Zhang, Susan F. Foley, Rashmi Kshirsagar, David Evans, Sha Mi, Werner Meier, R. Blake Pepinsky

Journal:

Analytical Biochemistry

Year:

2010

Language:

english

File:

PDF, 796 KB

english, 2010

3

Comparative biological responses to human Sonic, Indian, and Desert hedgehog

Suji Pathi, Sylvia Pagan-Westphal, Darren P Baker, Ellen A Garber, Paul Rayhorn, David Bumcrot, Clifford J Tabin, R Blake Pepinsky, Kevin P Williams

Journal:

Mechanisms of Development

Year:

2001

Language:

english

File:

PDF, 794 KB

english, 2001

4

Structural and Functional Differences Between Glycosylated and Non-glycosylated Forms of Human Interferon-β (IFN-β)

Laura Runkel, Werner Meier, R. Blake Pepinsky, Michael Karpusas, Adrian Whitty, Kathleen Kimball, Margot Brickelmaier, Celine Muldowney, Wendy Jones, Susan E. Goelz

Journal:

Pharmaceutical Research

Year:

1998

File:

PDF, 1.35 MB

1998

5

A Small Molecule Very Late Antigen–4 Antagonist Can Inhibit Ovalbumin-induced Lung Inflammation

Koo, Gloria C., Shah, Kashmira, Ding, Gloria J. F., Xiao, Jianying, Wnek, Richard, Doherty, George, Tong, Xin Chun, Pepinsky, R. Blake, Lin, Ko-Chung, Hagmann, William K., Kawka, Douglas, Singer, Irwi

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2003

Language:

english

File:

PDF, 635 KB

english, 2003

6

Most cleaved anti-Müllerian hormone binds its receptor in human follicular fluid but little is competent in serum

Pierre, Alice, Racine, Chrystèle, Rey, Rodolfo, Fanchin, Renato, Taieb, Joëlle, Cohen-Tannoudji, Joëlle, Carmillo, Paul, Pepinsky, R. Blake, Cate, Richard L., di Clemente, Nathalie

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2016

Language:

english

File:

PDF, 2.02 MB

english, 2016

7

Meteorin reverses hypersensitivity in rat models of neuropathic pain

Jesper Roland Jørgensen, Xiao-Jun Xu, H. Moore Arnold, Gordon Munro, Jing-Xia Hao, Blake Pepinsky, Carol Huang, Bang Jian Gong, Zsuzsanna Wiesenfeld-Hallin, Lars U. Wahlberg, Teit E. Johansen

Journal:

Experimental Neurology

Year:

2012

Language:

english

File:

PDF, 530 KB

english, 2012

8

GFRalpha3 is expressed predominantly in nociceptive sensory neurons

Olivia E. Orozco, Lee Walus, Dinah W. Y. Sah, R. Blake Pepinsky, Michele Sanicola

Journal:

European Journal of Neuroscience

Year:

2001

Language:

english

File:

PDF, 280 KB

english, 2001

9

Tat-mediated protein delivery can facilitate MHC class I presentation of antigens

Pamela Moy, Yasmin Daikh, Blake Pepinsky, David Thomas, Steve Fawell, James Barsoum

Journal:

Molecular Biotechnology

Year:

1996

Language:

english

File:

PDF, 1.49 MB

english, 1996

10

Investigating the Role of Artemin Glycosylation

Danwen, Qiu, Code, Christian, Quan, Chao, Gong, Bang-Jin, Arndt, Joseph, Pepinsky, Blake, Rand, Kasper D., Houde, Damian

Journal:

Pharmaceutical Research

Year:

2016

Language:

english

File:

PDF, 3.65 MB

english, 2016

11

An lmmunoassay to Detect Human Mullerian Inhibiting Substance in Males and Females during Normal Development

HUDSON, PETER L., DOUGAS, IRENE, CATE, RICHARD L., EPSTEIN, JAMES, PEPINSKY, R. BLAKE, MACLAUGHLIN, DAVID T.

Journal:

Obstetric and Gynecologic Survey

Year:

1990

Language:

english

File:

PDF, 160 KB

english, 1990

12

Augmented desensitization to epidermal growth factor (EGF) immediate actions: A novel mechanism for altered EGF growth response in mutant A431 cells

Avraham Karasik, Sethu S.-K. Reddy, R. Blake Pepinsky, Tommy Brock, C. Ronald Kahn

Journal:

Journal of Cellular Physiology

Year:

1990

Language:

english

File:

PDF, 505 KB

english, 1990

13

Tat-Mediated Delivery of Heterologous Proteins into Cells

Stephen Fawell, Joe Seery, Yasmin Daikh, Claire Moore, Chen, Blake Pepinsky and James Barsoum

Journal:

Proceedings of the National Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 1.42 MB

english, 1994

14

A prodomain fragment from the proteolytic activation of growth differentiation factor 11 (GDF11) remains associated with the mature growth factor and keeps it soluble

Pepinsky, R. Blake, Gong, Bang Jian, Gao, Yan, Lehmann, Andreas, Ferrant, Janine, Amatucci, Joseph, Sun, Yaping, Bush, Martin, Walz, Thomas, Pederson, Nels, Cameron, Thomas, Wen, Dingyi

Journal:

Year:

2017

Language:

english

File:

PDF, 2.72 MB

english, 2017

15

Sphingosine 1-phosphate receptor modulator fingolimod (FTY720) does not promote remyelination in vivo

Yinghui Hu, Xinhua Lee, Benxiu Ji, Kevin Guckian, Daniel Apicco, R. Blake Pepinsky, Robert H. Miller, Sha Mi

Journal:

Molecular and Cellular Neuroscience

Year:

2011

Language:

english

File:

PDF, 1.86 MB

english, 2011

16

Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β

Arndt, Joseph W., Qian, Fang, Smith, Benjamin A., Quan, Chao, Kilambi, Krishna Praneeth, Bush, Martin W., Walz, Thomas, Pepinsky, R. Blake, Bussière, Thierry, Hamann, Stefan, Cameron, Thomas O., Weinr

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 5.59 MB

english, 2018

17

Tissue distribution of 35S-metabolically labeled neublastin (BG00010) in rats

Penner, Natalia, Purushothama, Shobha, Pepinsky, Blake

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2020

Language:

english

File:

PDF, 2.57 MB

english, 2020

18

Crystal structure of the α1β1 integrin I-domain: insights into integrin I-domain function

Matthias Nolte, R.Blake Pepinsky, Sergei Yu. Venyaminov, Victor Koteliansky, Philip J. Gotwals, Michael Karpusas

Journal:

Year:

1999

Language:

english

File:

PDF, 772 KB

english, 1999

19

Stimulation of Pancreatic Islet Beta-Cell Replication by Oncogenes

Michael Welsh, Nils Welsh, Thomas Nilsson, Per Arkhammar, R. Blake Pepinsky, Donald F. Steiner and Per-Olof Berggren

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 947 KB

english, 1988

20

Disulfide Structure of the Leucine-Rich Repeat C-Terminal Cap and C-Terminal Stalk Region of Nogo-66 Receptor

Wen, Dingyi, Wildes, Craig P., Silvian, Laura, Walus, Lee, Mi, Sha, Lee, Daniel H. S., Meier, Werner, Pepinsky, R. Blake

Journal:

Year:

2005

Language:

english

File:

PDF, 339 KB

english, 2005

21

Long-acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model

R. Blake Pepinsky, Renee I. Shapiro, Shaoshan Wang, Abhijit Chakraborty, Alan Gill, Doreen J. Lepage, Dingyi Wen, Paul Rayhorn, Gerald S.B. Horan, Frederick R. Taylor, Ellen A. Garber, Alphonse Galdes

Journal:

Journal of Pharmaceutical Sciences

Year:

2002

Language:

english

File:

PDF, 189 KB

english, 2002

22

Effect of combined treatment with methylprednisolone and soluble Nogo-66 receptor after rat spinal cord injury

Benxiu Ji, Mingwei Li, Stephane Budel, R. Blake Pepinsky, Lee Walus, Thomas M. Engber, Stephen M. Strittmatter, Jane K. Relton

Journal:

European Journal of Neuroscience

Year:

2005

Language:

english

File:

PDF, 505 KB

english, 2005

23

Production of a PEGylated Fab′ of the anti-LINGO-1 Li33 Antibody and Assessment of Its Biochemical and Functional Properties in Vitro and in a Rat Model of Remyelination

Pepinsky, R. Blake, Walus, Lee, Shao, Zhaohui, Ji, Benxiu, Gu, Sheng, Sun, Yaping, Wen, Dingyi, Lee, Xinhua, Wang, Qin, Garber, Ellen, Mi, Sha

Journal:

Bioconjugate Chemistry

Year:

2011

Language:

english

File:

PDF, 3.38 MB

english, 2011

24

Specific Inhibition of a Human Papillomavirus E2 Trans -Activator by Intracellular Delivery of Its Repressor

PEPINSKY, R. BLAKE, ANDROPHY, ELLIOT J., CORINA, KAREN, BROWN, RHONDA, BARSOUM, JAMES

Journal:

DNA and Cell Biology

Year:

1994

Language:

english

File:

PDF, 3.76 MB

english, 1994

25

A Direct Binding Assay for the Vascular Cell Adhesion Molecule-1 (VCAM1) Interaction with α4 Integrins

Lobb, Roy R., Antognetti, Giovanna, Pepinsky, R. Blake, Burkly, Linda C., Leone, Diane R., Whitty, Adrian

Journal:

Cell Communication and Adhesion

Year:

1995

Language:

english

File:

PDF, 1.09 MB

english, 1995

26

LINGO-1 Regulates Oligodendrocyte Differentiation through the Cytoplasmic Gelsolin Signaling Pathway

Shao, Zhaohui, Lee, Xinhua, Huang, Guanrong, Sheng, Guoqing, Henderson, Christopher E., Louvard, Daniel, Sohn, Jiho, Pepinsky, Blake, Mi, Sha

Journal:

Journal of Neuroscience

Year:

2017

Language:

english

File:

PDF, 4.90 MB

english, 2017

27

Suppression of sodium dodecyl sulfate–polyacrylamide gel electrophoresis sample preparation artifacts for analysis of IgG4 half-antibody

Frederick R. Taylor, Holly L. Prentice, Ellen A. Garber, Hans A. Fajardo, Elena Vasilyeva, R. Blake Pepinsky

Journal:

Analytical Biochemistry

Year:

2006

Language:

english

File:

PDF, 215 KB

english, 2006

28

The Plasma and Cytoplasmic Forms of Human Gelsolin Differ in Disulfide Structure †

Wen, Dingyi, Corina, Karen, Chow, E. Pingchang, Miller, Stephan, Janmey, Paul A., Pepinsky, R. Blake

Journal:

Year:

1996

Language:

english

File:

PDF, 704 KB

english, 1996

29

Functional Characterization of Integrin α6β4 Adhesion Interactions Using Soluble Integrin Constructs Reveals the Involvement of Different Functional Domains in the β4 Subunit

Chen, Ling Ling, Gabarra, Veronica, Cho, Samuel, Browning, Beth, Cao, Xianjun, Huet, Heather, Cheung, Anne, Morena, Ron, Ramirez, Miriam, Shields, Michael, Blake Pepinsky, R., McLachlan, Karen

Journal:

Cell Communication and Adhesion

Year:

2008

Language:

english

File:

PDF, 484 KB

english, 2008

30

Pathophysiologic Role of α4 Integrins in the Lung

ROY R. LOBB, WILLIAM M. ABRAHAM, LINDA C. BURKLY, ALAN GILL, WEINING MA, JAMES A. KNIGHT, DIANE R. LEONE, GIOVANNA ANTOGNETTI, R. BLAKE PEPINSKY

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 596 KB

english, 1996

31

A Cell-Free Electrochemiluminescence Assay for Measuring β1-Integrin–Ligand Interactions

Paul H. Weinreb, William J. Yang, Shelia M. Violette, Megan Couture, Kathleen Kimball, R.Blake Pepinsky, Roy R. Lobb, Serene Josiah

Journal:

Analytical Biochemistry

Year:

2002

Language:

english

File:

PDF, 127 KB

english, 2002

32

LINGO-1 antagonist promotes functional recovery and axonal sprouting after spinal cord injury

Benxiu Ji, Mingwei Li, Wu-Tian Wu, Leung-Wah Yick, Xinhua Lee, Zhaohui Shao, Joy Wang, Kwok-Fai So, John M. McCoy, R. Blake Pepinsky, Sha Mi, Jane K. Relton

Journal:

Molecular and Cellular Neuroscience

Year:

2006

Language:

english

File:

PDF, 1.40 MB

english, 2006

33

LINGO-1 regulates oligodendrocyte differentiation by inhibiting ErbB2 translocation and activation in lipid rafts

Lee, Xinhua, Shao, Zhaohui, Sheng, Guoqing, Pepinsky, Blake, Mi, Sha

Journal:

Molecular and Cellular Neuroscience

Year:

2014

Language:

english

File:

PDF, 1.27 MB

english, 2014

34

Comparative Assessment of the Ligand and Metal Ion Binding Properties of Integrins α9β1 and α4β1

Pepinsky, R. Blake, Mumford, Richard A., Chen, Ling Ling, Leone, Diane, Amo, Suzanne E., Riper, Gail Van, Whitty, Adrian, Dolinski, Brian, Lobb, Roy R., Dean, Dennis C., Chang, Linda L., Raab, Conrad

Journal:

Year:

2002

Language:

english

File:

PDF, 245 KB

english, 2002

35

Development and validation of immunoassays to quantify the half-antibody exchange of an IgG4 antibody, natalizumab (Tysabri®) with endogenous IgG4

Renée I. Shapiro, Tatiana Plavina, Brian R. Schlain, R. Blake Pepinsky, Ellen A. Garber, Matthew Jarpe, Paula S. Hochman, Nancy G. Wehner, Frederique Bard, Ruth Motter, Ted A. Yednock, Frederick R. Ta

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2011

Language:

english

File:

PDF, 654 KB

english, 2011

36

Endothelial cell lymphocyte function-associated antigen-3 and an unidentified ligand act in concert to provide costimulation to human peripheral blood CD4+ T cells

Caroline O.S. Savage, Christopher C.W. Hughes, R.Blake Pepinsky, Barbara P. Wallner, Arnold S. Freedman, Jordan S. Pober

Journal:

Cellular Immunology

Year:

1991

Language:

english

File:

PDF, 973 KB

english, 1991

37

Artemin promotes functional long-distance axonal regeneration to the brainstem after dorsal root crush

Wong, Laura Elisabeth, Gibson, Molly E., Arnold, H. Moore, Pepinsky, Blake, Frank, Eric

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.29 MB

english, 2015

38

Ubiquitin in avian leukosis virus particles

Dan Putterman, R.Blake Pepinsky, Volker M. Vogt

Journal:

Year:

1990

Language:

english

File:

PDF, 1.30 MB

english, 1990

39

Detection of VAC-β (annexin-8) in human placenta

R.Blake Pepinsky, Rudolf Hauptmann

Journal:

Year:

1992

Language:

english

File:

PDF, 728 KB

english, 1992

40

Inhibition of LINGO-1 promotes functional recovery after experimental spinal cord demyelination

Zhang, Yongjie, Zhang, Yi Ping, Pepinsky, Blake, Huang, Guanrong, Shields, Lisa B.E., Shields, Christopher B., Mi, Sha

Journal:

Experimental Neurology

Year:

2015

Language:

english

File:

PDF, 1.03 MB

english, 2015

41

Blocking LINGO-1 Function Promotes Retinal Ganglion Cell Survival Following Ocular Hypertension and Optic Nerve Transection

Fu, Qing-Ling, Hu, Bing, Wu, Wutian, Pepinsky, R. Blake, Mi, Sha, So, Kwok-Fai

Journal:

Investigative Ophthalmology & Visual Science

Year:

2008

Language:

english

File:

PDF, 769 KB

english, 2008

42

Recombinant GDNF: Tetanus toxin fragment C fusion protein produced from insect cells

Jianhong Li, Ru-Ju Chian, Ilknur Ay, Samuel A. Celia, Brenda B. Kashi, Eric Tamrazian, Jonathan C. Matthews, Mary P. Remington, R. Blake Pepinsky, Paul S. Fishman, Robert H. Brown Jr., Jonathan W. Fra

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 461 KB

english, 2009

43

Oligodendrocyte differentiation and myelination defects in OMgp null mice

Xinhua Lee, Yinghui Hu, Yiping Zhang, Zhongshu Yang, Zhaohui Shao, Mengsheng Qiu, Blake Pepinsky, Robert H. Miller, Sha Mi

Journal:

Molecular and Cellular Neuroscience

Year:

2011

Language:

english

File:

PDF, 2.06 MB

english, 2011

44

Determination of the Disulfide Structure of Murine Meteorin, a Neurotrophic Factor, by LC–MS and Electron Transfer Dissociation-High-Energy Collisional Dissociation Analysis of Proteolytic Fragments

Wen, Dingyi, Xiao, Yongsheng, Vecchi, Malgorzata M., Gong, Bang Jian, Dolnikova, Jana, Pepinsky, R. Blake

Journal:

Analytical Chemistry

Year:

2017

Language:

english

File:

PDF, 693 KB

english, 2017

45

Improving the solubility of anti-LINGO-1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis

R. Blake Pepinsky, Laura Silvian, Steven A. Berkowitz, Graham Farrington, Alexey Lugovskoy, Lee Walus, John Eldredge, Allan Capili, Sha Mi, Christilyn Graff, Ellen Garber

Journal:

Protein Science

Year:

2010

Language:

english

File:

PDF, 616 KB

english, 2010

46

Crystallization and preliminary crystallographic analysis of the N-terminal two domain fragment of vascular cell adhesion molecule-1 (VCAM-1)

Jia-huai Wang, Blake Pepinsky, Michael Karpusas, Jin-huan Liu, Laurelee Osborn

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1994

Language:

english

File:

PDF, 415 KB

english, 1994

47

Ontogeny of epidermal growth factor receptor and lipocortin-1 in fetal and neonatal human lungs

Mahlon D. Johnson, Mary E. Gray, Graham Carpenter, R.Blake Pepinsky, Mildred T. Stahlman

Journal:

Human Pathology

Year:

1990

Language:

english

File:

PDF, 10.77 MB

english, 1990

48

Artemin Crystal Structure Reveals Insights into Heparan Sulfate Binding ‡

Silvian, Laura, Jin, Ping, Carmillo, Paul, Boriack-Sjodin, P. Ann, Pelletier, Carolyn, Rushe, Mia, Gong, BangJian, Sah, Dinah, Pepinsky, Blake, Rossomando, Anthony

Journal:

Year:

2006

Language:

english

File:

PDF, 1.04 MB

english, 2006

49

10.1038/89083

Pola, Roberto, Ling, Leona E., Silver, Marcy, Corbley, Michael J., Kearney, Marianne, Blake Pepinsky, R., Shapiro, Renee, Taylor, Frederick R., Baker, Darren P., Asahara, Takayuki, Isner, Jeffrey M.

Journal:

Nature Medicine

Year:

2001

Language:

english

File:

PDF, 1.08 MB

english, 2001

50

PEGylated Interferon Beta-1a: Meeting an Unmet Medical Need in the Treatment of Relapsing Multiple Sclerosis

Baker, Darren P., Pepinsky, Robert Blake, Brickelmaier, Margot, Gronke, Robert S., Hu, Xiao, Olivier, Kenneth, Lerner, Michaela, Miller, Larisa, Crossman, Mary, Nestorov, Ivan

Journal:

Journal of Interferon & Cytokine Research

Year:

2010

Language:

english

File:

PDF, 280 KB

english, 2010

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